Active skincare ingredients
  • 4-Butylresorcinol
  • Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

4-Butylresorcinol 99.0%

The Ultimate Melanin Root Inhibitor for Targeted Spot Correction

4-Butylresorcinol (also known as 4-n-Butylresorcinol) is a highly potent cosmetic grade brightening agent recognized for its superior ability to inhibit melanin synthesis at the root. Benchmarked as more effective than many traditional whitening agents, including Phenylethyl Resorcinol (377), it serves as a specialized active ingredients skincare solution for addressing melasma and stubborn dark spots.

CAS No.

18979-61-8

Source

High-Purity Cosmetic Synthesis

Appearance Color

White to Off-white Crystalline Powder

Key Parameter

Purity ≥ 99.0%

Solubility

Oil-Soluble / Alcohol-Soluble

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

High-Purity 4-Butylresorcinol (≥ 99.0%): Farnesol-Free Dual-Enzyme Brightening Active

Formulating elite hyperpigmentation correctors and professional spot-treatment lines requires lipophilic dual-enzyme inhibitors that suppress melanogenesis at the molecular source without triggering contact dermatitis, formula discoloration, or oxidative instability. Manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade 4-Butylresorcinol is meticulously refined to maintain a strict 100% farnesol-free profile.

By concurrently inhibiting both Tyrosinase and Peroxidase enzymes within the melanogenesis pathway, this ultra-pure crystalline active intercepts pigment synthesis at multiple checkpoints, delivering clinical-grade radiance and pigment clearance for hyper-reactive skin architectures.

Clinical Efficacy & Pharmacological Performance (MoA)

  • Dual-Enzyme Blockade: Actively targets and suppresses both tyrosinase and peroxidase activity, blocking the enzymatic conversion of tyrosine into melanin at the source.

  • Clinical Pigment Clearance: Clinically documented to deliver a visible reduction in the intensity of stubborn dark spots and localized pigment clusters within an 8-week continuous application protocol.

  • Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key epidermal sensitivity markers within 48 hours, establishing an impeccable safety profile for compromised barriers.

Technical Data & Physical Specifications Engineered to eliminate manufacturing friction for OEM/ODM innovators, this high-purity crystalline powder dissolves smoothly into suitable cosmetic solvents or heated oil phases, yielding an absolute water-white, odorless profile that ensures zero formulation browning.

ParameterSpecification & Standard
INCI Name4-Butylresorcinol
CAS Number18979-61-8
Farnesol ContentN.D. (Limit of Detection < 1ppm)
Purity Assay≥ 99.0% (HPLC Verified)
AppearanceUltra-pure white to off-white crystalline powder
Odor ProfileOdorless (Scent-neutral)
Melting Point51.0°C – 54.0°C
Heavy Metals (Pb, As, Hg, Cd)< 10 ppm

Formulation Directives & Synergistic Matrices As a lipophilic active, 4-Butylresorcinol requires pre-dissolution in compatible cosmetic glycols (such as Propanediol or Butylene Glycol) before integration. To prevent heat degradation, incorporation during the cool-down phase at temperatures below 45°C is strongly recommended.

Target ApplicationRecommended DosageCompanion Actives & Mechanistic Synergy
Targeted Spot Correctors0.2% – 0.5%Active + Allantoin: Combines dual-enzyme melanin suppression with water-soluble cellular micro-trauma healing to rapidly fade localized pigment clusters.
SOS Barrier Brightening0.1% – 0.3%Active + Panthenol: Panthenol floods the stratum corneum with deep hydration, creating a non-reactive environment for enzymatic binding without dryness.
Translucent Radiance Care0.3% – 0.5%Active + Ceramide NP: Halts melanogenesis from within while Ceramide NP physically reconstructs the depleted surface lipid cement for absolute barrier protection.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring absolute batch-to-batch consistency and complete regulatory transparency, we streamline compliance filings for global personal care brands.

Procurement ParameterFulfillment Details
Minimum Order Quantity (MOQ)1 kg (Optimized for laboratory R&D trials and pilot batch productions)
Global CertificationsISO 9001, ISO 22000, COSMOS Approved standards, HALAL
Quality DocumentationBatch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and purity testing reports provided with all shipments.
Logistics & DeliveryFactory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules.

Accelerate Your R&D Pipeline Stop compromising on formula instability, oxidized brightening agents, and ingredient-induced skin irritation. Secure your supply chain with our factory-direct, highly purified dual-enzyme inhibitors and empower your next formulation with medical-grade spot correction.

  • Request a Free R&D Sample for immediate formulation compatibility and sensory evaluation.

  • Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).

  • Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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