Licorice derived active ingredients manufacturer

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

Bisabolol

The Gold Standard Oil-Soluble Active for Gentle and Effective Soothing

Bisabolol, specifically the alpha-isomer, is a high-purity cosmetic grade monocyclic sesquiterpene alcohol. Originally derived from German Chamomile, it is celebrated as a “classic” in dermatology for its exceptional safety profile and potent anti-inflammatory properties. Its oil-soluble nature allows it to integrate seamlessly into the skin’s lipid barrier, providing deep-seated relief from irritation, redness, and environmental stress.

CAS No.	515-69-5 (Natural) / 23089-26-1 (Synthetic)
Source	High-Purity Synthesis / Botanical Extraction
Appearance Color	Colorless to Viscous Clear Liquid
Key Parameter	Purity ≥ 95.0% / Free from Farnesol
Solubility	Oil-Soluble / Soluble in Ethanol and Glycols

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

High-Purity Farnesol-Free Bisabolol: Zero-Sensitization Active for Dermo-Cosmetics

Formulating for compromised skin barriers requires precise molecular control. Engineered by Shaanxi Huatai Bio-Fine Chemicals Co., our Farnesol-Free Bisabolol eliminates the allergen risks commonly associated with crude chamomile derivatives. This active rapidly suppresses epidermal hyper-reactivity, offering formulators a water-white, completely odorless solution for highly sensitive skin applications.

Clinical Efficacy Benchmarks In-vivo assessments confirm that this purified active intercepts the inflammatory cascade by suppressing key irritation mediators (such as PGE2 and IL-1α). Application on chemically or UV-induced erythema demonstrates up to a 40% reduction in visible redness and accelerates barrier recovery time within a strict 48-hour window.

Core Technical Data & Specifications

Parameter	Specification & Standard
INCI Name	Bisabolol
CAS Number	515-69-5 (Natural) / 23089-26-1 (Synthetic)
Farnesol Content	N.D. (Limit of Detection < 1ppm)
Purity Level (GC)	≥ 95.0% (High-Purity Grade)
Appearance	Colorless to light yellow viscous liquid (Water-white)
Odor Profile	Odorless to trace characteristic woody scent
Heavy Metals	< 10 ppm
Recommended Dosage	0.1% – 0.5% (Daily Care) / Up to 1.0% (Acute SOS Repair)
Formulation Phase	Oil-soluble (Incorporate into oil phase or cool-down phase <45°C)

Grade Selection Guide for Procurement To support diverse market positioning and budget requirements, we supply three distinct specifications:

Product Grade	Sourcing Origin	Strategic Formulation Target
Natural Alpha-Bisabolol (≥95%)	Botanical Extraction	Premium “Clean Beauty”, Baby Care, Post-Procedure Care
Natural Alpha-Bisabolol (≥85%)	Botanical Extraction	Standard Sensitive Skin Lines, Cost-balanced Natural Claims
Synthetic Bisabolol (≥95%)	Chemical Synthesis	Mass-Market Skincare, Sunscreens, Daily Barrier Maintenance

Formulation Superiority for OEM/ODM Unlike standard soothing agents, our engineered Bisabolol exhibits extreme heat stability and a pH tolerance ranging from 3.0 to 11.0. Its absolute lack of color and scent ensures it will never interfere with the aesthetic or olfactory profile of your final emulsion or anhydrous systems.

Synergistic Repair Matrices Deploy this active as a biological penetration enhancer to amplify the efficacy of your existing formulations:

Companion Active	Mechanistic Synergy	Target Application
Bisabolol + Allantoin	Combines lipid-based inflammation suppression with aqueous cellular regeneration.	Micro-trauma healing & Post-laser recovery creams
Bisabolol + Panthenol	Dual-pathway rescue: soothes cutaneous neuro-receptors while flooding the stratum corneum with hydration.	After-sun relief gels & Intense barrier serums
Bisabolol + Ceramide NP	Halts internal erythema while physically reconstructing the depleted epidermal lipid cement.	Chronic redness & Rosacea defense lotions

Supply Chain Transparency & Global Compliance Manufactured under stringent factory-direct protocols, every batch from Shaanxi Huatai Bio-Fine Chemicals Co. guarantees absolute traceability. Our production facilities hold advanced global certifications including ISO, COSMOS, and HALAL. Full regulatory dossiers are readily available to streamline your international compliance filings.

Frequently Asked Questions

1. What is the standard MOQ and delivery timeline?

Our Minimum Order Quantity (MOQ) is set at 1kg to support R&D and pilot runs. Global fulfillment for in-stock inventory is processed and dispatched via air freight (FedEx/DHL) within 3-5 working days.

2. Are full regulatory documents provided with each batch?

Yes. A comprehensive technical package—including the Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and rigorous HPLC/GC chromatograms—accompanies every shipment to guarantee your QA standards.

3. Does your Bisabolol dissolve in water?

No, it is strictly oil-soluble. It is highly soluble in cosmetic oils, lower alcohols, and glycols. For optimal stability, we recommend incorporating it during the cooling phase of your manufacturing process at temperatures below 45°C.

4. Can I request materials for lab trials?

We actively support global formulators. 10-20g complimentary R&D samples are available for your compatibility and stability testing (purchaser covers international shipping only).

Accelerate Your R&D: Request Pricing & Samples

Secure your supply chain with our factory-direct active ingredients. Upgrade your next SOS Repair or sensitive skin formula with the industry standard in soothing efficacy.

Contact our technical sales team to request your Free 20g R&D Sample.
Download the full Technical Dossier (COA, MSDS, TDS).
Receive a customized Bulk Volume Quote today.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Product-related information

Why choose us

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.