China Ceramide NP (Ceramide 3) Suppliers & Manufacturer

CAS No.	100403-19-8
Source	High-Purity Bio-fermentation (Yeast-derived)
Appearance Color	White to Off-white Crystalline Powder
Key Parameter	Purity ≥ 95.0% / Skin-Identical Structure
Solubility	Oil-Soluble (requires heating) / Dispersible in Lipids

CAS No.

100403-19-8

Source

High-Purity Bio-fermentation (Yeast-derived)

Appearance Color

White to Off-white Crystalline Powder

Key Parameter

Purity ≥ 95.0% / Skin-Identical Structure

Solubility

Oil-Soluble (requires heating) / Dispersible in Lipids

High-Purity Ceramide NP: Farnesol-Free Lipid Active

Formulating dermatological barrier repair systems requires skin-identical lipid replenishment without introducing contact allergens. Manufactured via advanced bio-fermentation by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Ceramide NP (formerly Ceramide 3) possesses a stereochemical structure identical to human skin ceramides.

Rigorously purified to maintain a strict 100% farnesol-free profile, this bioactive lipid integrates directly into the intercellular lamellae. It physically reconstructs compromised stratum corneum integrity, drastically downregulating Transepidermal Water Loss (TEWL) and blocking environmental irritant penetration in atopic and hyper-reactive skin.

Clinical Efficacy & Pharmacological Performance

Barrier Reconstruction: In-vivo assessments demonstrate significant improvements in stratum corneum hydration and structural barrier integrity within a 7-day continuous application protocol.
Erythema Reduction: Clinically validated to reduce visible skin redness and inflammation markers by 30% over 14 days.
Mechanical Tension: Visibly increases epidermal elasticity by restoring the lipid matrix that supports keratinocyte cohesion.

Grade Selection Guide (Formulation Formats) To eliminate manufacturing friction caused by the high melting point of pure ceramides, we supply both the high-purity crystalline powder and advanced pre-dispersed liquid systems for cold-process integration:

Product Grade	INCI Nomenclature	Application & Processing Function
Pure Ceramide NP Powder	Ceramide NP	≥ 95.0% purity. Ideal for intensive barrier creams and balms. Requires heating (85°C–90°C) in the oil phase for proper dissolution.
Water-Dispersible Liposomal Liquid	Ceramide NP (and) Hydrogenated Lecithin (and) Glycerin (and) Water	Pre-solubilized complex designed for clear toners, light serums, and cold-process manufacturing. Prevents recrystallization.

Technical Data & Physical Specifications Engineered for absolute aesthetic neutrality, our purified Ceramide NP ensures zero interference with the final color or olfactory profile of your emulsion.

Parameter	Specification & Standard
INCI Name	Ceramide NP
CAS Number	100403-19-8
Farnesol Content	N.D. (Limit of Detection < 1ppm)
Appearance (Powder)	Refined white crystalline powder
Odor Profile	Odorless (Scent-neutral)
Melting Point (Powder)	85°C – 95°C
pH Stability Range	Exceptionally stable between 4.0 – 8.0
Heavy Metals (Pb, As, Hg, Cd)	< 10 ppm

Formulation Directives & Synergistic Matrices Ceramide NP acts as the foundational structural defense, amplifying the restorative efficacy of companion actives in complex emulsion systems.

Target Application	Recommended Dosage	Companion Actives & Mechanistic Synergy
Biomimetic Lipid Repair	0.1% – 1.0%	Ceramide NP + Cholesterol + Free Fatty Acids: Formulated at the physiological 3:1:1 molar ratio, this complex replicates the native lipid bilayer for maximum long-term resilience.
SOS Barrier Sealing	0.05% – 0.5%	Ceramide NP + Panthenol: Panthenol floods the deep stratum corneum with targeted hydration, while Ceramide NP creates a waterproof intercellular seal to halt TEWL.
Post-Procedure Recovery	0.2% – 1.0%	Ceramide NP + Allantoin: Combines the physical surface reconstruction of lipids with the water-soluble cellular micro-trauma healing of Allantoin to instantly calm erythema.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By isolating skin-identical molecules via sustainable bio-fermentation, we provide absolute regulatory transparency for global personal care brands.

Procurement Parameter	Fulfillment Details
Minimum Order Quantity (MOQ)	100g to 1kg (Dependent on specific grade; highly accessible for R&D trials and pilot batches)
Global Certifications	ISO, COSMOS, HALAL
Quality Documentation	Batch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and HPLC purity testing reports provided with all shipments.
Logistics & Packaging	Factory-direct global shipping via air freight. Stable shelf life of 24 months when stored tightly sealed away from heat and light.

Accelerate Your R&D Pipeline Stop compromising on formulation recrystallization, structural instability, and ingredient-induced sensitization. Secure your supply chain with our factory-direct, highly purified bio-fermented ceramides and empower your next formulation with medical-grade barrier repair.

Request a Free R&D Sample for immediate formulation compatibility and stability testing.
Download the Full Technical Dossier (COA, MSDS, TDS, and Processing Guidelines).
Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.