Fisetin
The Senolytic Breakthrough for Clearing “Zombie Cells” and Skin Rejuvenation
Fisetin is a naturally occurring flavonol and a powerful cosmetic grade active at the forefront of European anti-aging research. As a premier “Senolytic” agent, it specifically targets and helps eliminate senescent cells—often called “zombie cells”—which accumulate with age and secrete inflammatory factors that damage surrounding healthy tissue.
| CAS No. | 528-48-3 |
|---|---|
| Source | High-Purity Botanical Extraction (Cotinus coggygria) |
| Appearance Color | Yellow Crystalline Powder |
| Key Parameter | Purity ≥ 98.0% |
| Solubility | Soluble in DMSO and Ethanol; Partially Water-Soluble |
Direct Factory Supply
Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.
Flexible OEM/ODM
Custom specifications for purity, solvent, and formulation tailored to your requirements.
Stable Supply Chain
Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.
Strict QA & Certs
ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.
High-Purity Fisetin (≥ 98.0%): Farnesol-Free Senolytic Longevity Active
Formulating elite biological age-management and cellular rejuvenation systems requires advanced botanical senolytics that selectively clear metabolic waste and senescent “zombie” cells without triggering contact dermatitis, rapid oxidation, or formulation discoloration. Extracted from Cotinus coggygria and manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Fisetin is meticulously refined to maintain a strict 100% farnesol-free profile.
By functioning as a potent senolytic agent that targets exhausted cellular populations, reduces the Senescence-Associated Secretory Phenotype (SASP), and activates SIRT1 longevity pathways, this high-purity active restores youthful dermal matrix architecture in hyper-reactive skin.
Clinical Efficacy & Pharmacological Performance (MoA)
Senolytic Clearance: Selectively induces apoptosis in senescent “zombie” cells, purging metabolic debris and suppressing chronic low-grade inflammation (SASP).
Matrix Density Enhancement: Clinically documented to significantly improve skin density, structural firmness, and dermal elasticity during continuous application.
Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key epidermal sensitivity markers within 48 hours, establishing an impeccable safety profile for compromised barriers.
Technical Data & Physical Specifications Engineered to eliminate manufacturing friction for OEM/ODM innovators, this high-purity flavonoid dissolves smoothly into suitable cosmetic solvents or heated oil phases, yielding an absolute water-white, odorless profile when pre-dissolved.
Formulation Directives & Synergistic Matrices As a naturally lipophilic flavonoid, Fisetin requires pre-dissolution in appropriate cosmetic glycols (such as Propanediol), ethanol, or carrier oils during the heated oil phase before integration.
Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring absolute batch-to-batch consistency and complete regulatory transparency, we streamline compliance filings for global personal care brands.
Accelerate Your R&D Pipeline Stop compromising on formula stability, product discoloration, and ingredient-induced skin irritation. Secure your supply chain with our factory-direct, highly purified cellular longevity actives and empower your next formulation with medical-grade anti-aging efficacy.
Request a Free R&D Sample for immediate formulation compatibility and sensory evaluation.
Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).
Access Customized Bulk Wholesale Pricing.
Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.
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