China Hydroxypinacolone Retinoate Suppliers & Manufacturer

CAS No.	893412-73-2
Source	High-Purity Cosmetic Synthesis
Appearance Color	Yellow to Orange Liquid (10% Solution) / Crystalline Powder
Key Parameter	Direct Receptor Binding / High Photostability
Solubility	Oil-Soluble

CAS No.

893412-73-2

Source

High-Purity Cosmetic Synthesis

Appearance Color

Yellow to Orange Liquid (10% Solution) / Crystalline Powder

Key Parameter

Direct Receptor Binding / High Photostability

Solubility

Oil-Soluble

High-Purity Hydroxypinacolone Retinoate (HPR): Farnesol-Free Direct-Acting Retinoid Active

Formulating advanced anti-aging and cellular renewal systems requires advanced retinoid derivatives that bind directly to cellular receptors without demanding complex metabolic conversion steps, thereby eliminating the severe erythema, peeling, and irritation typical of traditional Vitamin A analogs. Manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Hydroxypinacolone Retinoate (HPR) is meticulously refined to maintain a strict 100% farnesol-free profile.

By directly activating Retinoic Acid Receptors (RARs), this high-purity lipophilic active accelerates epidermal turnover and stimulates collagen synthesis, providing professional anti-wrinkle efficacy for hyper-reactive and sensitive skin architectures.

Clinical Efficacy & Pharmacological Performance (MoA)

Rapid Wrinkle Reduction: Clinically documented to deliver a visible reduction in superficial and deep wrinkle depth within a 2 to 4-week continuous application protocol.
Elasticity Enhancement: Demonstrates a significant, measurable increase in skin firmness and overall elasticity during standard in-vivo testing frameworks.
Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key epidermal sensitivity markers within 48 hours, establishing an impeccable safety profile for delicate barriers.

Grade Selection Guide & Technical Specifications To accommodate diverse emulsion and anhydrous manufacturing requirements, we supply both ultra-pure crystalline powder and a standardized liquid solution:

Parameter & Grade Configuration	Specification & Standard
INCI Name	Hydroxypinacolone Retinoate (and) Dimethyl Isosorbide
CAS Number	893556-20-6
Farnesol Content	N.D. (Limit of Detection < 1ppm)
Available Configurations	99% Pure Crystalline Powder OR 10% Stabilized Cosmetic Solution (HPR10)
Appearance & Odor	Refined white powder / Clear, water-white liquid (Odorless, scent-neutral)
pH Range Stability	Exceptionally stable between 5.0 – 7.0
Heavy Metals (Pb, As, Hg, Cd)	< 10 ppm

Formulation Directives & Synergistic Matrices Exhibits exceptional thermal and oxidative stability compared to standard retinol. Incorporate directly into the oil phase or during the cool-down stage at temperatures below 40°C.

Target Application	Recommended Dosage	Companion Actives & Mechanistic Synergy
Targeted Anti-Aging Serums	0.1% – 2.0% (10% Solution) / 0.01% – 0.1% (Pure Powder)	HPR + Allantoin: Combines direct RAR activation with water-soluble cellular micro-trauma healing to rapidly smooth texture without flaking.
SOS Barrier Renewal	0.5% – 1.5% (10% Solution)	HPR + Panthenol: Panthenol floods the renewed epidermis with deep hydration, creating a non-reactive environment for collagen synthesis.
Structural Firming Care	1.0% – 2.0% (10% Solution)	HPR + Ceramide NP: Reduces fine lines from within while Ceramide NP physically reconstructs the depleted surface lipid cement.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring absolute batch-to-batch consistency and complete regulatory transparency, we streamline compliance filings for global personal care brands.

Procurement Parameter	Fulfillment Details
Minimum Order Quantity (MOQ)	1 kg (Optimized for laboratory R&D trials and pilot batch productions)
Global Certifications	ISO 9001, ISO 22000, COSMOS Approved standards, HALAL
Quality Documentation	Batch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and purity testing reports provided with all shipments.
Logistics & Delivery	Factory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules.

Accelerate Your R&D Pipeline Stop compromising on formula instability, retinoid-induced contact irritation, and complex encapsulation requirements. Secure your supply chain with our factory-direct, highly stable direct-acting retinoids and empower your next formulation with medical-grade anti-aging efficacy.

Request a Free R&D Sample for immediate formulation compatibility and sensory evaluation.
Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).
Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.