Active skincare ingredients
  • Oil-Soluble Glabridin 90%
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Factory
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Exhibition
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd.

Oil-Soluble Glabridin 90%

The Natural Whitening Gold and Potent Tyrosinase Inhibitor

Oil-Soluble Glabridin 90% is a premium whitening active ingredient extracted from the root of Glycyrrhiza glabra. Known in the industry as “whitening gold,” Oil-Soluble Glabridin 90% offers exceptional skin penetration capabilities and highly effective skin brightening. Its core advantages include superior oil solubility for cosmetic formulations, high safety and gentleness without blackthorn irritation, and the ability to inhibit melanin at the source. It is one of the most potent natural inhibitors of tyrosinase currently available for high-end whitening and brightening products.

INCI Name

Glabridin

CAS No.

59870-68-7

Source

Natural Botanical (Licorice Root)

Appearance

White powder

Core Function

Tyrosinase Inhibition, Whitening, Anti-inflammatory, Brightening, Melanin Blocking.

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

High-Purity Oil-Soluble Glabridin 90%: Farnesol-Free Dermal Brightening Active

Formulating elite brightening and hyperpigmentation correctors requires lipophilic tyrosinase inhibitors that deliver profound clinical efficacy without destabilizing lipid phases or inducing contact sensitization. Extracted from Glycyrrhiza glabra roots and manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Oil-Soluble Glabridin is rigorously refined to maintain a strict 100% farnesol-free profile.

Known throughout the industry as the “Whitening Gold,” this active binds firmly to the active center of tyrosinase via hydrogen bonding, blocking tyrosine entry and intercepting melanin synthesis at the cellular level for superior clinical results.

Clinical Efficacy & Pharmacological Performance (MoA)

  • Enzymatic Blockade: Acts deep within the epidermal basal layer to inhibit tyrosinase activity, effectively halting melanin production at the source.

  • Cellular Potency: B16-F10 melanoma cell evaluations confirm an IC50 value of 18.36 μ\mumol/L, correlating with robust inhibition and high biological activity.

  • Thermal & Solubility Stability: Demonstrates exceptional resilience under accelerated stress testing, maintaining structural integrity across temperature ranges from -18°C to 48°C and dissolving cleanly into carrier oils (e.g., camellia oil).

Technical Data & Physical Specifications Engineered to eliminate manufacturing friction for OEM/ODM innovators, this high-purity crystalline powder dissolves smoothly into heated oil phases or compatible cosmetic glycols.

ParameterSpecification & Standard
INCI NameGlycyrrhiza Glabra (Licorice) Root Extract / Glabridin
CAS Number59870-68-7
Farnesol ContentN.D. (Limit of Detection < 1ppm)
Purity Assay≥ 90.0% (HPLC Verified)
AppearanceWhite crystalline powder
Odor ProfileOdorless (Scent-neutral; advanced purification applied)
Solubility ProfileOil-soluble and lipophilic
Heavy Metals (Pb, As, Hg, Cd)< 10 ppm

Formulation Directives & Synergistic Matrices Glabridin 90% integrates seamlessly into lipid systems, serving as the cornerstone for advanced brightening night creams, sun care shields, and targeted spot correctors.

Target ApplicationRecommended DosageCompanion Actives & Mechanistic Synergy
Targeted Spot Correctors0.2% – 0.5%Glabridin + Niacinamide: Combines deep tyrosinase blocking with melanosome transfer inhibition for multi-pathway hyperpigmentation correction.
Brightening Night Creams0.1% – 0.3%Glabridin + Alpha-Arbutin: Dual-action melanin suppression optimized for nocturnal repair cycles.
Sun Care Support0.05% – 0.2%Glabridin + Vitamin C Derivatives: Mitigates UV-induced erythema while neutralizing free radicals to prevent post-inflammatory hyperpigmentation.
Processing GuidelinesN/ADissolve into the heated oil phase during emulsification or pre-dissolve in compatible cosmetic glycols before aqueous integration.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to international cosmetic safety benchmarks, ensuring complete traceability and regulatory transparency for global personal care brands.

Procurement ParameterFulfillment Details
Minimum Order Quantity (MOQ)1 kg (Highly accessible for laboratory R&D trials and pilot batch runs)
Global CertificationsISO 9001, ISO 22000, COSMOS Approved standards, HALAL, IQNET
Quality DocumentationBatch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and HPLC purity testing reports provided with all shipments.
Logistics & DeliveryFactory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules.

Accelerate Your R&D Pipeline Stop compromising on formulation instability, crude extract discoloration, and sub-optimal brightening efficacy. Secure your supply chain with our factory-direct, highly purified botanical actives and empower your next formulation with gold-standard tyrosinase inhibition.

  • Request a Free R&D Sample for immediate formulation compatibility and stability testing.

  • Download the Full Technical Dossier (COA, MSDS, TDS, and Clinical Efficacy Reports).

  • Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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