Licorice derived active ingredients manufacturer

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

Pyrrolidinyl Diaminopyrimidine Oxide

The Follicle Revitalizer for Intensive Anti-Hair Loss and Regrowth Support

Pyrrolidinyl Diaminopyrimidine Oxide is a high-performance cosmetic grade active and a benchmark in modern trichology. Closely related in structure to Minoxidil, it acts as a potent follicle revitalizer that increases blood flow to the scalp and reverses the shrinkage of hair follicles. By improving nutrient delivery and oxygenation, it effectively reduces hair shedding and stimulates the growth of thicker, stronger hair.

CAS No.	55921-65-8
Source	High-Purity Cosmetic Synthesis
Appearance Color	White to Off-white Crystalline Powder
Key Parameter	Purity ≥ 99.0% / Highly Effective Follicle Activation
Solubility	Soluble in Ethanol, Propylene Glycol; Slightly Water-Soluble

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

High-Purity Pyrrolidinyl Diaminopyrimidine Oxide (≥ 99.0%): Farnesol-Free Follicle Anchor

Formulating advanced hair density and anti-thinning tonics requires active ingredients that stimulate microcirculation and prevent perifollicular fibrosis without inducing scalp irritation or systemic side effects. Manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Pyrrolidinyl Diaminopyrimidine Oxide is rigorously refined to maintain a strict 100% farnesol-free profile, eliminating the risk of contact sensitization on hyper-reactive scalps. By anchoring hair roots and prolonging the anagen (growth) phase, this high-purity active revitalizes miniaturized follicles and reduces shedding, offering a compliance-friendly cosmetic alternative to traditional pharmaceutical treatments.

Clinical Efficacy & Pharmacological Performance (MoA)

Shedding Reduction: Clinically documented to decrease hair shedding by 30% over a 12-week continuous application protocol.
Density Enhancement: Demonstrates a visible, measurable increase in overall hair density and shaft thickness within standard testing frameworks.
Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key scalp irritation markers within 48 hours, eliminating the flaking and dryness associated with harsh scalp tonics.

Technical Data & Physical Specifications Engineered to eliminate manufacturing friction for OEM/ODM innovators, this ultra-fine crystalline powder dissolves cleanly to yield an absolute water-white, odorless profile, ensuring zero residue or aesthetic alteration in hydro-alcoholic tonics.

Parameter	Specification & Standard
INCI Name	Pyrrolidinyl Diaminopyrimidine Oxide
CAS Number	55940-06-8
Farnesol Content	N.D. (Limit of Detection < 1ppm)
Purity (Assay)	≥ 99.0% (HPLC Verified)
Appearance	Ultra-fine white crystalline powder
Odor Profile	Odorless (Scent-neutral)
Loss on Drying	≤ 0.5%
pH Stability Range	Exceptionally stable between 5.5 – 7.5
Heavy Metals (Pb, As, Hg, Cd)	< 10 ppm

Formulation Directives & Synergistic Matrices This active exhibits exceptional stability in hydro-alcoholic or aqueous-glycolic systems, integrating seamlessly into modern scalp care architectures.

Target Application	Recommended Dosage	Companion Actives & Mechanistic Synergy
Anti-Thinning Tonics	0.5% – 3.0%	Active + Allantoin: Combines targeted follicle vasodilation with water-soluble cellular micro-trauma healing to instantly soothe inflamed, stressed scalps.
Intensive Density Serums	2.0% – 5.0%	Active + Panthenol: Panthenol floods the stratum corneum with hydration, creating a non-reactive environment for the active to extend the anagen phase without drying.
Scalp Barrier Recovery	1.0% – 4.0%	Active + Ceramide NP: Tackles internal follicle miniaturization from within, while Ceramide NP physically reconstructs the scalp’s depleted lipid cement on the surface.
Processing Guidelines	N/A	Pre-dissolve completely in the solvent phase (such as Ethanol or Propylene Glycol) prior to final aqueous phase integration below 50°C.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring the complete absence of pharmaceutical contaminants and trademarked structural aliases, we provide absolute regulatory transparency for global personal care brands.

Procurement Parameter	Fulfillment Details
Minimum Order Quantity (MOQ)	1 kg (Optimized for laboratory R&D trials and pilot batch productions)
Global Certifications	ISO, COSMOS, HALAL
Quality Documentation	Batch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and HPLC purity chromatograms provided with all shipments.
Logistics & Delivery	Factory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules.

Accelerate Your R&D Pipeline Stop compromising on formula stability, greasy residues, and ingredient-induced scalp irritation. Secure your supply chain with our factory-direct, highly purified follicle-anchoring actives and empower your next anti-thinning formulation with medical-grade efficacy.

Request a Free R&D Sample for immediate formulation compatibility and stability testing.
Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).
Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Product-related information

Why choose us

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.