Spermidine HCl
The Autophagy Inducer for Deep Cellular Self-Cleaning and Renewal
Spermidine HCl is a potent cosmetic grade polyamine and a breakthrough in longevity-focused skincare. It acts as a primary inducer of autophagy—the natural process of cellular self-cleaning—allowing skin cells to break down and recycle damaged components, thereby restoring youthful function and vitality.
| CAS No. | 334-50-9 |
|---|---|
| Source | High-Purity Synthesis / Botanical Extraction |
| Appearance Color | White to Off-white Crystalline Powder |
| Key Parameter | Purity ≥ 98.0% |
| Solubility | Highly Water-Soluble |
Direct Factory Supply
Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.
Flexible OEM/ODM
Custom specifications for purity, solvent, and formulation tailored to your requirements.
Stable Supply Chain
Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.
Strict QA & Certs
ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.
High-Purity Spermidine HCl (≥ 98.0%): Farnesol-Free Cellular Autophagy Active
Formulating elite biological longevity and cellular rejuvenation lines requires advanced polyamine derivatives that induce deep intracellular recycling without introducing contact dermatitis, formula discoloration, or stability degradation. Manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Spermidine HCl is meticulously refined to maintain a strict 100% farnesol-free profile.
By functioning as a potent physiological autophagy inducer, this high-purity active clears cellular metabolic debris and damaged organelles from within, protecting mitochondrial networks and reversing biological aging markers in hyper-reactive skin architectures.
Clinical Efficacy & Pharmacological Performance (MoA)
Autophagic Cellular Recycling: Triggers targeted autophagy to purge metabolic waste and “cellular clutter,” restoring youthful intracellular metabolic activity.
Barrier & Density Enhancement: Clinically documented to significantly enhance skin barrier function and visibly improve overall skin density and elasticity over a 6-week continuous application protocol.
Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key epidermal sensitivity markers within 48 hours, establishing an impeccable safety profile for compromised barriers.
Technical Data & Physical Specifications Engineered to eliminate manufacturing friction for OEM/ODM innovators, this water-soluble crystalline powder dissolves cleanly into aqueous systems, yielding an absolute crystal-clear, water-white, and odorless profile.
| Parameter | Specification & Standard |
| INCI Name | Spermidine Hydrochloride |
| CAS Number | 334-50-9 |
| Farnesol Content | N.D. (Limit of Detection < 1ppm) |
| Purity Assay (HPLC) | ≥ 98.0% (Guaranteed high biological and autophagy activity) |
| Appearance | High-purity crystalline powder |
| Odor Profile | Odorless (Scent-neutral) |
| Loss on Drying | ≤ 1.0% |
| pH Range Stability | Exceptionally stable between 4.5 – 6.5 |
| Heavy Metals (Pb, As, Hg, Cd) | < 10 ppm |
Formulation Directives & Synergistic Matrices Highly water-soluble and engineered for effortless integration. Incorporate directly into the aqueous phase of emulsions or clear serum systems during the cooling stage to preserve peak bioactivity.
| Target Application | Recommended Dosage | Companion Actives & Mechanistic Synergy |
| Cellular Cleanup Serums | 0.01% – 0.5% | Spermidine HCl + Allantoin: Combines targeted autophagy and metabolic waste clearance with water-soluble micro-trauma healing to rapidly soothe fatigued skin. |
| SOS Barrier Revival | 0.05% – 0.2% | Spermidine HCl + Panthenol: Panthenol floods the epidermis with targeted hydration, creating a non-reactive environment for Spermidine HCl to reboot mitochondrial function. |
| Age-Reversal Emulsions | 0.1% – 0.5% | Spermidine HCl + Ceramide NP: Restores youthful metabolic activity from within while Ceramide NP physically reconstructs the depleted surface lipid cement for absolute barrier protection. |
Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring absolute batch-to-batch consistency and complete regulatory transparency, we streamline compliance filings for global personal care brands.
| Procurement Parameter | Fulfillment Details |
| Minimum Order Quantity (MOQ) | Flexible baseline configurations (Highly accessible for laboratory R&D trials and pilot batch runs) |
| Global Certifications | ISO, COSMOS Approved standards, HALAL |
| Quality Documentation | Batch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and HPLC purity testing reports provided with all shipments. |
| Logistics & Delivery | Factory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules. |
Accelerate Your R&D Pipeline Stop compromising on formula stability, product discoloration, and ingredient-induced skin irritation. Secure your supply chain with our factory-direct, highly purified cellular longevity actives and empower your next formulation with medical-grade anti-aging efficacy.
Request a Free R&D Sample for immediate formulation compatibility and sensory evaluation.
Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).
Access Customized Bulk Wholesale Pricing.
Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.
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