Active skincare ingredients
  • Thioctic Acid
  • Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

Thioctic Acid

The Universal Antioxidant for Comprehensive Protection and Anti-Glycation

Thioctic Acid, also known as Alpha Lipoic Acid (ALA), is a premier cosmetic grade active often referred to as the “Universal Antioxidant.” Its unique amphiphilic nature allows it to function in both water and oil phases of the skin, providing unparalleled protection against oxidative damage while simultaneously inhibiting the glycation process that leads to skin yellowing and loss of elasticity.

CAS No.

1077-28-7

Source

High-Purity Cosmetic Synthesis

Appearance Color

Light Yellow Crystalline Powder

Key Parameter

Purity ≥ 99.0% / Amphiphilic Solubility

Solubility

Water & Oil Soluble (Amphiphilic)

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

High-Purity Thioctic Acid (Alpha Lipoic Acid): Farnesol-Free Universal Antioxidant Active

Formulating elite anti-aging and anti-glycation systems requires versatile universal antioxidants that neutralize free radicals across both lipid and aqueous cellular matrices without introducing sulfur-like odors, sensitization, or stability degradation. Manufactured via advanced purification and fractional refinement by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Thioctic Acid is meticulously processed to maintain a strict 100% farnesol-free profile.

Acting as a supreme biological antioxidant recycler, this high-purity crystalline active inhibits Advanced Glycation End-product (AGE) cross-linking, reverses sallow skin tones, and restores mitochondrial vitality in hyper-reactive skin architectures.

Clinical Efficacy & Pharmacological Performance (MoA)

  • Anti-Glycation Defense: Actively inhibits the formation of Advanced Glycation End-products (AGEs), preventing collagen cross-linking and mitigating skin stiffness and dullness.

  • Radiance & Anti-Yellowing: Clinically documented to demonstrate a significant reduction in skin “yellowing” (bb value) and a marked increase in luminosity within a 4-week continuous application protocol.

  • Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key epidermal sensitivity markers within 48 hours, establishing an impeccable safety profile for compromised barriers.

Technical Data & Physical Specifications Engineered to completely eliminate the sulfur odors and formulation bottlenecks associated with standard alpha lipoic acid, this ultra-pure crystalline powder dissolves smoothly into versatile phases, ensuring refined sensory compatibility.

ParameterSpecification & Standard
INCI NameThioctic Acid (Alpha Lipoic Acid)
CAS Number1077-28-7
Farnesol ContentN.D. (Limit of Detection < 1ppm)
Purity Assay (HPLC)≥ 99.0% (Guaranteed high biological potency)
AppearanceHigh-purity white to off-white crystalline powder
Odor ProfileOdorless (Advanced refining applied to minimize sulfur notes)
Melting Point60.0°C – 62.0°C
pH Range StabilityExceptionally stable between 5.0 – 7.0
Heavy Metals (Pb, As, Hg, Cd)< 10 ppm

Formulation Directives & Synergistic Matrices Exhibits versatile solubility across both oil and water phases. To preserve peak antioxidant integrity, integrate during the final cooling stage of manufacturing at temperatures below 40°C.

Target ApplicationRecommended DosageCompanion Actives & Mechanistic Synergy
Urban Defense Serums0.1% – 1.0%Thioctic Acid + Allantoin: Combines universal free-radical scavenging with water-soluble micro-trauma healing to rapidly soothe pollution-stressed skin.
SOS Barrier Revival0.5% – 2.0%Thioctic Acid + Panthenol: Panthenol floods the stratum corneum with targeted hydration, creating a non-reactive environment to reverse sallow skin tones.
Anti-Aging Emulsions1.0% – 5.0% (Professional)Thioctic Acid + Ceramide NP: Inhibits AGE formation from within while Ceramide NP physically reconstructs the depleted surface lipid cement.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring absolute batch-to-batch consistency and complete regulatory transparency, we streamline compliance filings for global personal care brands.

Procurement ParameterFulfillment Details
Minimum Order Quantity (MOQ)1 kg (Optimized for laboratory R&D trials and pilot batch productions)
Global CertificationsISO, COSMOS Approved standards, HALAL
Quality DocumentationBatch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and HPLC purity testing reports provided with all shipments.
Logistics & DeliveryFactory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules.

Accelerate Your R&D Pipeline Stop compromising on formula stability, sallow skin tones, and ingredient-induced skin irritation. Secure your supply chain with our factory-direct, highly purified antioxidant actives and empower your next formulation with medical-grade anti-glycation efficacy.

  • Request a Free R&D Sample for immediate formulation compatibility and sensory evaluation.

  • Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).

  • Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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