Licorice derived active ingredients manufacturer

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

Urolithin A

The Mitochondrial Autophagy Specialist for Restoring Youthful Cellular Energy

Urolithin A is a breakthrough cosmetic grade metabolite and a cornerstone of “Mito-Aging” research. It is the only known natural compound capable of inducing mitophagy—the selective recycling of damaged mitochondria—allowing skin cells to regain the metabolic energy levels of much younger tissue.

CAS No.	1143-70-0
Source	High-Purity Synthesis / Natural Precursor Refinement
Appearance Color	Pale Yellow to Off-white Crystalline Powder
Key Parameter	Purity ≥ 98.0%
Solubility	Soluble in DMSO and Ethanol; Lipophilic

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

High-Purity Urolithin A (≥ 98.0%): Farnesol-Free Mitophagy & Cellular Energy Active

Formulating elite biological longevity and age-reversal systems requires advanced lipophilic metabolites that trigger selective mitophagy and clear dysfunctional cellular powerhouses without introducing contact dermatitis, formula discoloration, or stability degradation. Manufactured by Shaanxi Huatai Bio-Fine Chemicals Co., our Cosmetic-Grade Urolithin A is meticulously refined to maintain a strict 100% farnesol-free profile.

By functioning as a first-in-class mitophagy activator, this high-purity active targets the root mechanisms of mitochondrial aging, recycling exhausted organelles and maximizing cellular ATP production in hyper-reactive skin architectures.

Clinical Efficacy & Pharmacological Performance (MoA)

Mitochondrial Recycling: Selectively induces mitophagy to clear damaged, ROS-producing mitochondria, restoring youthful metabolic activity.
Dermal Density Enhancement: Clinically documented to significantly improve skin density, structural resilience, and visibly reduce fine lines through accelerated cellular energy restoration.
Sensitivity Downregulation: Pharmacological evaluations confirm a 40% reduction in key epidermal sensitivity markers within 48 hours, establishing an impeccable safety profile for compromised barriers.

Technical Data & Physical Specifications Engineered to eliminate manufacturing friction for OEM/ODM innovators, this high-purity lipophilic active dissolves smoothly into appropriate cosmetic glycols or heated oil phases, yielding an absolute water-white, odorless profile.

Parameter	Specification & Standard
INCI Name	Urolithin A
CAS Number	1143-70-0
Farnesol Content	N.D. (Limit of Detection < 1ppm)
Purity Assay (HPLC)	≥ 98.0% (Guaranteed high biological and mitophagy activity)
Appearance	High-purity crystalline form
Odor Profile	Odorless (Scent-neutral)
Loss on Drying	≤ 1.0%
pH Range Stability	Exceptionally stable between 5.0 – 7.0
Heavy Metals (Pb, As, Hg, Cd)	< 10 ppm

Formulation Directives & Synergistic Matrices As a lipophilic compound, Urolithin A requires pre-dissolution in suitable cosmetic glycols, carrier oils, or the heated oil phase during emulsification to ensure optimal integration and bioavailability.

Target Application	Recommended Dosage	Companion Actives & Mechanistic Synergy
Cellular Energy Serums	0.05% – 0.5%	Urolithin A + Allantoin: Combines targeted mitophagy with water-soluble micro-trauma healing to rapidly clear dead cellular waste in fatigued skin.
SOS Barrier Revival	0.1% – 0.3%	Urolithin A + Panthenol: Panthenol floods the stratum corneum with targeted hydration, creating a non-reactive environment for Urolithin A to reboot the mitochondrial pool.
Age-Reversal Emulsions	0.2% – 0.5%	Urolithin A + Ceramide NP: Restores youthful metabolic activity from within while Ceramide NP physically reconstructs the depleted surface lipid cement for absolute barrier protection.

Procurement, Compliance & Supply Chain Shaanxi Huatai adheres strictly to global cosmetic safety benchmarks. By ensuring absolute batch-to-batch consistency and complete regulatory transparency, we streamline compliance filings for global personal care brands.

Procurement Parameter	Fulfillment Details
Minimum Order Quantity (MOQ)	1 kg (Optimized for laboratory R&D trials and pilot batch productions)
Global Certifications	ISO 9001, ISO 22000, COSMOS Approved standards, HALAL
Quality Documentation	Batch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and HPLC purity testing reports provided with all shipments.
Logistics & Delivery	Factory-direct global shipping via air freight ensures rapid delivery for uninterrupted production schedules.

Accelerate Your R&D Pipeline Stop compromising on formula stability, product discoloration, and ingredient-induced skin irritation. Secure your supply chain with our factory-direct, highly purified cellular energy actives and empower your next formulation with medical-grade anti-aging efficacy.

Request a Free R&D Sample for immediate formulation compatibility and sensory evaluation.
Download the Full Technical Dossier (COA, MSDS, TDS, and Safety Reports).
Access Customized Bulk Wholesale Pricing.

Contact our technical sales team directly to initiate your procurement request and secure factory-direct allocations today.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Product-related information

Why choose us

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.